Researchers@Brown

Video dipak raj
  1. Raj DK, Das BR, Dash AP and Supakar PC. Identification of telomerase activity in gametocytes of Plasmodium falciparum. Biochemical and Biophysical Research Communication. 2003; 309 (3): 685-8.
  2. Raj DK, Das BR, Dash AP and Supakar PC. Genetic diversity in MSA-1 gene of Plasmodium falciparum in different malaria endemic localities. American Journal of Tropical Medicine and Hygiene 2004;71 (3):285-9.
  3. Raj DK, Das BR, Dash AP and Supakar PC. Detection of a rare point mutation in the C-terminus conserve region of MSA-1 gene in Plasmodium falciparum. Experimental Parasitology 2004;106 (1-2): 45-49.
  4. Mishra K, Raj DK, Dash AP and Hazra RK. Combined detection of Brugia malayi and Wuchereria bancrofti using single PCR. Acta Troica. 2005; 93(3): 233-7.
  5. Mishra K, Raj DK, Dash AP and Hazra RK. A simple Para film based membrane-feeding method for in vivo radioisotope labeling of polypeptide in mosquitoes. Annals of Tropical Medicine and Parasitology 2005;99(8) 803-806.
  6. Raj DK, Mishra S, Das BR and Dash AP. Plasmodium falciparum Pfs25 gene promoter has no polymorphism in natural isolates of Eastern India Acta Protozologica 2005; 44, 289-292.
  7. Mishra S, Raj DK, Dash AP, and Supakar PC. An efficient detection of chloroquine resistance marker in pfCRT gene of Plasmodium falciparum by PCR-SSCP analysis in eastern Indian isolates. Transaction of Royal Society of Tropical Medicine and Hygiene 2006;100(3): 243-7.
  8. Mishra K, Raj DK, Hazra RK, Dash AP and Supakar PC. The development and evaluation of a single step multiplex PCR method for simultaneous detection of Brugia malayi and Wuchereria bancrofti. Mol Cell Probes. 2007;21: 355-62.
  9. Raj DK, Mu J, Jiang H, Kabat J, Singh S, Sullivan M, Fay MP, McCutchan TF, Su XZ. Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PFMRP) alters its fitness and transport of antimalarial drugs and glutathione. Journal of Biological Chemistry 2010;Mar 20; 284(12):7687-96.
  10. Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, Miura K, Yuan J, Tanaka TQ, Johnson RL, Jiang H, Huang R, Williamson K, Lambert LE, Long C, Austin CP, Wu Y and Su XZ. A Class of Tricyclic Compounds Blocking Malaria Oocyst Development and Transmission. Antimicrobial Agents and Chemotherapy 2012;Jan;57(1):425-35.
  11. Raj DK, Nixon CP, Nixon CE, Dvorin JD, DiPetrillo CG, Pond-Tor S, Wu HW, Jolly G, Pischel L, Lu A, Michelow IC, Cheng L, Conteh S, McDonald EA, Absalon S, Holte SE, Friedman JF, Fried M, Duffy PE and Kurtis JD. Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection. Science 2014;344:871-7. PMID24855263.

PATENTS

  1. Su XZ, Yuan J, Raj DK, Pattaradilokart S, Jonshon R and Huang R. “COMPOUND THAT TREAT MALARIA AND PREVENT MALARIA TRANSMISSION” International patent PCT/US2010/047019, Pub. No. WO/2011/025969, March, 03,2011.
  2. Raj DK, Su XZ, Pattaradilokart S, Jonshon R, Huang R, Su XZ “COMPOUND THAT TREAT MALARIA AND PREVENT MALARIA TRANSMISSION” U.S Patent 13 392668, Pub. No. US2012/0196882A1, August, 02,2012.
  3. Kurtis J, Duffy P, Christian N, Raj DK, Friedman J, Fried M. “VACCINE FOR FALCIPARUM MALARIA” International patent PCT/US2012/067404, Pub. No. WO/2011/025969, June, 06,2013.

BOOKS AND BOOK CHAPTERS

Raj DK & Sobti RC. Carbohydrate Antigens. Biotech Bulletin, 1998:( 6) 17-27.

MANUSCRIPTS IN PREPARATION

Raj DK, Nixon CE, Dvorin JD, Pond-Tor S, Wu HW, Jolly G, Cheng L, McDonald EA, Friedman JF, Fried M, Duffy PE and Kurtis JD. Antibodies to Plasmodium falciparum glutamic acid rich protein (PfGARP) inhibit parasite growth by arresting trophozoite development.

ABSTRACTS

  1. Raj DK, Das BR, Dash AP & Supakar Plasmodium falciparum Pfs25 gene polymorphism in natural isolates, 6th International Symposium on Vectors & Vector Borne Diseases, Feb, 9-11, 2002, Bhubaneswar, India.
  2. Raj DK, Das BR, Dash AP & Supakar PC Genetic polymorphisms in MSA-1 gene of Plasmodium falciparum in different malaria endemic localities. 6th International Symposium on Vectors & Vector Borne Diseases, Feb, 9-11, 2002, Bhubaneswar, India.
  3. Raj DK, Das BR, Dash AP and Supakar PC, Detection of telomerase activity in the gametocyte ofPlasmodium falciparum. Indo-US joint venture for development of Science, Dec. 21-22, 2003 , Bangalore, INDIA
  4. Raj DK, Das BR, Dash AP & Supakar PC, Detection of rare point mutations in the C-terminus region of MSA-1 gene in Plasmodium falciparum. Malaria Symposium, Nov. 12 – 14, 2002, Delhi India.
  5. Mishra S, Raj DK, Supakar PC, Hazra RK, Das B & Dash AP, An efficient detection of chloroquine resistance marker in pfCRT gene of Plasmodium falciparum from complicated malaria samples by PCR-SSCP analysis. International Conference on Malaria: Laveran to Genomics, Nov. 4-6, 2005, New Delhi, India.
  6. Raj DK, Mu J, Sullivan M, Su XZ, Searching for potential vaccine candidate in the hypothetical genes of Plasmodium falciparum by looking at the repetitive sequence and membrane spanning domain in Plasmodium falciparum, malaria meeting, March 20-21, 2006, Baltimore, USA.
  7. Raj DK, Mu J, Jiang H, Karat, Sullivan M, Fay MP, McCutchan TF, Su XZ, and Disruption of a putative ABC transporter alters its growth and response to anti-malarial drugs. ASTMH meeting, Nov. 4-8, 2007, Philadelphia, PA, USA.
  8. Raj DK, Nixon CP, Fried M, Duffy PE, Jolly G and Kurtis JD, Identification of vaccine candidates for pediatric falciparum Malaria. Lifespan 19th Hospital Research Celebration, Oct. 27, 2011,Providence, RI, USA.
  9. Raj DK, Nixon CP, Fried M, Duffy PE, and Kurtis JD, Vaccine Candidate Identification for pediatric falciparum malaria. ASTMH meeting, Dec. 4-8, 2011,Philadelphia, PA, USA.
  10. Yuan J, Eastman RT, Pattaradilokrat S, Raj DK, Cheng KCC, Johnson RL, Huang R, Liu A, Guha R, Inglese J, Willium TE, Austin CP and Su XZ, Chemical genomics for antimalarial drug combinations, The Molecular Approaches to Malaria meeting Feb. 2012, 19-23,Lorne, Australia
  11. Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, Miura K, Yuan J, Tanaka TQ, Johnson RL, Jiang H, Huang R, Williamson K, Lambert LE, Long C, Austin CP, Wu Y and Su XZ. (2012), A Class of Tricyclic Compounds Blocking Malaria Oocyst Development and Transmission. Genomic Epidemiology of Malaria Conference, June 10-13, 2012, Sanger Institute, Hinxton, Cambridge, UK
  12. Dipak K. Raj, Christian P. Nixon, Sunthorn Pond-Tor, Hai-Wei Wu, Grant Jolly, Lauren Pischel, Ailin Lu, Christina Nixon, Ian Michelow, Ling Cheng, Jennifer F. Friedman, Michal Fried, Patrick E. Duffy, Jonathan D. Kurtis., Vaccination with Schizont Egress Antigen-1 protects mice from P. berghei ANKA challenge. ASTMH meeting, Nov.13-17, 2013 Washington, D.C., USA
  13. Dipak K. Raj, Christina Nixon, Sunthorn Pond-Tor, Hai-Wei Wu, Grant Jolly, Jennifer F. Friedman, Michal Fried, Patrick E. Duffy, Jonathan D. Kurtis., Antibodies to Plasmodium falciparum glutamic acid rich protein (PfGARP) inhibit parasite growth by arresting trophozoite development. ASTMH meeting, Nov.13-17, 2013 Washington, D.C., USA
  14. Dipak K. Raj, Christian P. Nixon, Sunthorn Pond-Tor, Hai-Wei Wu, Grant Jolly, Lauren Pischel, Ailin Lu, Christina Nixon, Ian Michelow, Ling Cheng, Jennifer F. Friedman, Michal Fried, Patrick E. Duffy, Jonathan D. Kurtis. Antibodies to Schizont Egress Antigen-1 (PfSEA-1) block schizont egress from falciparum infected RBCs. ASTMH meeting, Nov.13-17, 2013 Washington, D.C., USA
  15. Dipak K. Raj, Christian P. Nixon, Sunthorn Pond-Tor, Hai-Wei Wu, Grant Jolly, Lauren Pischel, Ailin Lu, Christina Nixon, Ian Michelow, Ling Cheng, Jennifer F. Friedman, Michal Fried, Patrick E. Duffy, Jonathan D. Kurtis. Antibodies to Schizont Egress Antigen-1 (PfSEA-1) predict resistance to severe falciparum malaria in children. ASTMH meeting, Nov.13-17, 2013 Washington, D.C., USA
  16. Christina E. Nixon, Rute C. Silva, Dipak K. Raj, Christian P. Nixon, Christen DiPetrillo, Jeffrey Dvorin, Jonathan D. Kurtis. The interactome of Schizont Egress Antigen-1, a novel vaccine candidate for falciparum malaria. Molecular and Cell Biology of Malaria, August 4-9, 2013, Lucca (Barga), Italy
  17. Christina E. Nixon, David Mulama, Dipak K. Raj, Sunthorn Pond-Tor, Jonathan D. Kurtis, Ann Moormann. Cellular immune responses to a novel malaria vaccine candidate, Pf Schizont Egress Antigen-1, in young children and adults. ASTMH meeting, Nov.13-17, 2013 Washington, D.C., USA
  18. Michelow IC, Raj DK, Nixon CP, Nixon CE, Nelson S, Tsai, S.W., Pond-Tor S, Federick, K., Friedman JF, Fried M, Duffy PE and Kurtis JD. Antibodies to a novel falciparum malaria antigen inhibit erythrocyte invasion. Lifespan Research Symposium 22, October 2, Abstract#22.
  19. Raj DK, Nixon CP, Pond-Tor S, Wu HW, Jolly G, Pischel L, Lu A, Nixon CE, Michelow I, Cheng L, Friedman JF, Fried M, Duffy PE, Kurtis JD. Vaccination with Schizont Egress Antigen-1 protects mice from P. berghei ANKA challenge. Lifespan Research Symposium 22, October 2, Abstract#22.
  20. Dipak DK, Nixon CP, Pond-Tor S, Wu HW, Jolly G, Friedman JF, Fried M, Duffy PE, Kurtis JD., Antibodies to Plasmodium falciparum glutamic acid rich protein (PfGARP) inhibit parasite growth by arresting trophozoite development. Lifespan Research Symposium 22, October 2, Abstract#22